•Johnny Galecki | played | Leonard Leakey Hofstadter (179Eps.) |
•Jim Parsons | played | Sheldon Lee Cooper (179Eps.) |
•Kaley Cuoco | played | Penny (176Eps.) |
•Simon Helberg | played | Howard Joel Wolowitz (178Eps.) |
•Kunal Nayyar | played | Rajesh Ramayan Koothrappali (178Eps.) |
•Mayim Bialik | played | Amy Farrah Fowler (Season 4-; recurring previously) (101Eps.) |
•Melissa Rauch | played | Bernadette Marianne Rostenkowski (Season 4, Episode 4-; recurring previously) (103Eps.) |
•Kevin Sussman | played | Stuart Bloom (Season 6, Episodes 1-13; recurring otherwise) (1Eps.) |
•Sara Gilbert | played | Leslie Winkle (Season 2; recurring otherwise) (4Eps.) |